Environmental Pollution Medical Conditions

Diseases caused by pollution may affect any of us with potentially devastating effects. According to a Cornell University study, about 40 percent of deaths worldwide are caused by environmental pollution (including water, air, and soil pollution) – see the article published by Chronicle Online on August 2, 2007. Knowing more about what causes these diseases and how they manifest will help us prevent or minimize exposure as well as identify pollution episodes and potential associated health diseases early. We hope that the general information provided here will help you in this respect.

Environmental Pollution Diseases

What Are Pollution Diseases and What Causes Them? Polluting the environment means spreading new man-made chemicals in the environment or re-distributing and concentrating natural substances/chemicals due to human activity. The main problem with pollution is that it may affect human health eventually resulting in medical conditions usually referred to as pollution diseases (since they would not have occurred in the absence of pollution). The health problems caused by pollution are not some rare types of illnesses happening to few exposed individuals, but rather they could be common and well-known diseases with symptoms as trivial as nausea, headache, cough, or difficulty in respiration! Additionally, pollution diseases are not affecting only people who directly handle pollutants; they may affect any one of us without even knowing it. This is because pollutant concentrations that should raise health concerns are usually not easily perceived by any of our senses, but may create long-term health effects.

Classifying Pollution Diseases

Below are the main pollution diseases classified based on the polluted media causing them – you can find more by clicking any of the links below:

Living Organisms Affected by Pollution Diseases as Indicators of Pollution

Living in a contaminated environment may sensitize the human body, weakening our defense against a large number of medical conditions, including cancers, arteriosclerosis, hepatitis, heart disease, asthma, and tuberculosis – to name just a few.

Plants and animals may also be affected and sometimes provide clues for pollution episodes:

  • banks of dead fish and/or birds along a water stream are an obvious sign of pollution, usually in high concentration)
  • trees are some of the “classic” indicators of environmental changes – which is the basis of using them to reconstruct past climates through the technique called dendrochronology. The basis of such technique is the fact that in most climates, trees develop growth rings every year. The width of the yearly rings is directly proportional to the amount of rain as well as any other environmental factors affecting tree growth (the wider the ring, the better condition the trees have), thus including pollution. Even if trees adapt and are still alive looking relatively healthy to the necked eye (when low concentrations of pollution is found in the vicinity of trees), by examining the width of each growth ring (in a tree core sample) one can observe pollution events;
  • overgrowth of algae is many times a clear sign of water pollution with fertilizers including nitrates and phosphates.
  • behavioral and other changes in fish and other animals – are usually associated with their exposure to endocrine disruptors and other chemicals.

Severe Medical Conditions Caused by Pollution

Mesothelioma

Did you know that environmental pollution can increase your risk of developing mesothelioma? Asbestos, a group of toxic minerals which occur naturally in the earth, has been heavily mined and employed by numerous industries in the U.S. throughout the last century, which resulted in unprecedented contamination. Multiple national and international agencies, including the U.S. Department of Health and Human Services and the International Agency for Research on Cancer, classify asbestos as a known human carcinogen.

Mesothelioma is a rare form of cancer which preponderantly affects the outer lining of the lungs, although it can develop in other regions of the body as well. Approximately 3,000 people in the U.S. are annually diagnosed with mesothelioma cancer. Exposure to asbestos is responsible for over 80% of mesothelioma cases. When fibers become airborne, they can easily be inhaled or ingested by whoever is in the proximity of the pollution source. The human body is not inherently designed to eliminate asbestos and thereby, particles which have accumulated in the lungs can cause severe inflammation in time and may subsequently lead to mesothelioma.

The Most Common Environmental Sources of Contamination:

  • Former asbestos or vermiculite mining sites
  • Old buildings
  • Construction and demolition sites

Skin Cancer

Skin cancer is the cancer of skin cells, consisting of changes in skin appearance or abnormal growth of skin cells in affected areas. The affected skin areas look different than the rest of the skin, involving skin growth (like bumps or mole-looking growth) of various types and/or rough areas of skin (of various colors) - with or without bleeding – that fail to heal or disappear. This type of cancer is easy to detect by our naked eye since it usually develops in the outermost layer of skin (also called epidermis). This is why only a minor percent of affected people actually die of skin cancer (with the exception of melanoma type discussed here).

Skin cancer is perceived as a direct result of prolonged sun exposure. Yet, many other risk factors exist, some of which may be – in specific cases - more prevalent than sun exposure. This explains the documented cases of skin cancer in areas with little to no exposure to the sun. Between the potential risk factors other than sun exposure, exposure to environmental pollution could substantially increase the risk of developing skin cancer regardless of sun exposure or other risk factors.

Skin Cancer: Melanoma

Melanoma is probably the most dangerous type of skin cancer, although it is a less common form of cancer (but its incidence is increasing). It occurs more in white people after the age of 60, but it may affect younger non-white people too. While melanoma may appear in any individual, there are certain well-defined situations enabling the identification of individuals at high risk for developing melanoma (mainly including: people with melanoma cases in the family, people with fair skin and/or a large number of moles and freckles, people with prolonged sun exposure episodes, and/or people exposed to certain environmental pollutants). Melanoma is usually manifested through skin lesions, moles or nodules which become cancerous resulting in asymmetrical shapes, changing colors, and rapidly evolving (e.g., in dimension). Because in most cases, there is no associated pain and it is usually hard to distinguish between non-cancerous and cancerous (melanoma) skin lesions, nodules, or moles – melanoma is considered asymptomatic. Nevertheless, some general distinctions have been pointed out mainly consisting of irregular and rapidly observable changes of existing skin conditions. Such distinctions are helpful for early identification and successful treatment of existing melanoma, as well as for prevention of future occurrences (by identifying high-risk individuals).

Melanoma seems to have a series of causes including:

  • Genetics – due to the genetically inherited material, people at higher risk of developing melanoma include those with one or more cases in the family as well as those with fair skin and/or a large number of moles.
  • Prolonged sun exposure – due to the exposure to UV radiation, many banal activities such as tanning, outdoor working and outdoor recreational activities and sports without protective clothes and sunscreen may result in various types of skin cancers including melanoma.
  • Pollution exposure - many types of skin cancers (although not necessarily melanoma) have been already linked to environmental pollution. Even though a clear link has not been established between pollutants and melanoma (a particular type of skin cancer), the potential of environmental pollutants to contribute to the development of this type of skin cancer exist. Pollution may act indirectly (by depleting the ozone layer protective to UV radiation) or directly through skin contact (e.g., polyaromatic hydrocarbons such as 7,12-dimethylbenz[a]anthracene (DMBA) – shown to have caused melanoma in experimental animals at high dose exposure).

While most melanomas are asymptomatic, there are a series of signs one can watch out for, which may indicate potential melanoma or potential for future melanoma development.

High-risk Symptoms

The following are indications (signs) of potential melanoma (please note that none of these signs necessarily imply melanoma and any of these signs may still be associated with non-cancerous skin conditions – however, these signs indicate a melanoma risk):

  • changes in existing moles and/or freckles (especially rapid changes) involving and resulting in one or more of the following:
    • variation in shape resulting in asymmetry
    • border irregularity and obscure demarcation;
    • variation in color (e.g., a mole with 3 or more colors)
    • increased size (over 6 mm)
    • evolving (changing) features
  • the appearance of rapidly evolving (growing) skin lesion, nodule and/or mole of various sizes, forms and colors; of higher concern should be:
    • sizes of 6 mm to several centimeters in diameter
    • asymmetric forms
    • various colors within one single feature (e.g., mole): including shades such as tan, dark brown, and black to blue, red and, light grey or uncolored (please note that an uncolored or unpigmented mole called amelanotic can also appear)
    • a new nodule which is growing and pigmented or vascular in appearance
    • itchy or tender skin lesions
    • skin lesions that may bleed and crust over
    • a spot or sore that fails to cure within 3 weeks
    • new pigmented line in a nail
    • something growing under a nail (especially pigment or vascular tissue)

If you experienced any of the above-mentioned signs/symptoms, it is highly recommended that you consult a dermatologist. As with any cancerous conditions, early detection is essential for successful melanoma treatment.

Low-risk Symptoms

While above we described signs and symptoms that usually indicate high melanoma risk, below are some reassuring signs, indicating a low melanoma risk and usually not requiring medical analysis (however, please always keep in mind that a low risk does not equal no risk and the only way to be certain is through medical control and analysis):

  • Slow, if at all, changes of any kind (e.g., in shape, color, form) in existing moles, nodules or skin lesions
  • Symmetrical shape and one color or no color
  • “Stuck on” appearance such as in the case of seborrhoeic warts

Individuals with High Risk for Developing Melanoma

High-risk individuals – more sensitive and prone to develop some type of melanoma - include:

  • Outdoor workers – including any type of outdoor activity, especially the agricultural workers, farmers, construction workers, road workers, outdoor patrols, gardeners and other professions involving prolonged outside activities;
  • Sensitive individuals – such as those with fair sun-sensitive skin (especially red- or blonde-haired people) and/or many freckles, people with many moles (100 or more) or atypical moles (5 or more), as well as those with an increased genetic risk
  • People who experienced blistering sunburn at young ages, especially repeated events over short period of time;
  • People who had prolonged and unprotected sun exposure during childhood years especially;
  • Older people (60 years or more) – mainly due to skin aging processes, which make the skin cells more sensitive to sunlight and more prone to develop moles and/or lesions which may eventually result in melanoma or other types of skin cancers.
  • People exposed to contamination (especially materials containing PAHs) may also be at high-risk for developing skin cancers, and potentially melanoma, too.

Note: Although, as shown above, some individuals are more sensitive and more at risk to develop melanoma than others, good preventive measures against melanoma are generally easy to apply and should be applied by all of us.

Other Medical Conditions Caused by Pollution

  • Liver cancerExposure to fine particulate matter may stimulate the growth of hepatic tumors through low-grade inflammation.
  • Colorectal cancer - A number of environmental factors, from food contamination to chlorinated water, may cause colorectal carcinoma.
  • Brain tumor - Air pollution has been linked to an increased risk of developing brain tumors.
  • Emphysema - It is practically a medical certainty that air pollution increases the risk of respiratory illnesses, including emphysema.
  • Heart diseases - The American Heart Association has linked exposure to air pollution to an increased risk of cardiovascular illness and mortality.
  • Atherosclerosis - Exposure to particulate matter pollution can trigger acute cardiovascular attacks
  • Hepatitis - Hepatitis A is an infectious disease known to be caused by, among other things, drinking from polluted water sources.
  • Lung cancer - Air pollution is known to increase the risk of developing respiratory illnesses and lung cancer.
  • Memory loss - Pollution particles can get into the brain and cause inflammation, further leading to depression, memory loss, and cognitive problems.
  • Leukemia - Traffic emissions, especially benzene, are known to be triggers of leukemia, especially in children.